MyBioSource.com's Dnmt3A/Dnmt3A2 Antibody (C-term) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The Dnmt3A/Dnmt3A2 Antibody (C-term) was generated using DNMT3A, and DNMT3A2 as the antigen and it reacts with Human, and Rat.
Description
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. DNMT3A is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated